Beyond this, there is currently not enough evidence to relate antibody levels to a level of immune response or immunity from COVID-19. a positive test, is associated with protection from a severe form of COVID-19. The presence of any detectable antibody i.e. We see values across this range and above. The range of positive values that can be measured by our vaccine immunity test is from 0.8 U/mL to 25,000 U/mL (U stands for units). ![]() ![]() The difference in antibody levels between individuals is not currently well understood. Understanding your vaccine immunity test result In a small number of cases, it may not always be possible to provide a result, please see our terms and conditions for details. ![]() Please collect and post your sample to us Monday-Thursday, to avoid delays over the weekend. Important: these tests are available for people aged over 18 only. There is currently not enough data to indicate whether or not a higher number of antibodies indicates a stronger immune response or a greater level of immunity. The COVID-19 vaccine immunity test will also provide a numerical value that indicates the amount of antibodies. A positive antibody result indicates that you have produced antibodies in response to the vaccine or past COVID-19 infection. All currently available vaccines use the spike protein to produce an immune response. This test will not provide you with a numerical value.ĬOVID-19 Vaccine Immunity Test: This test looks for COVID-19 spike protein antibodies in a blood sample. A positive antibody result indicates that you have had the COVID-19 virus in the past. Antibodies are made by the body in response to the virus. This test bundle combines our two COVID-19 antibody tests:ĬOVID-19 Antibody Test: This test looks for COVID-19 antibodies in a blood sample. Conclusion: We suggest specific adjusted thresholds (BAU/ml) for the four commercial antibody assays that are used to assess pre-exposure prophylaxis in immunocompromised patients.ROYAL MAIL TRACKED 24 SAMPLE RETURN INCLUDED Overall concordance increased consistently after applying new thresholds, i.e., 148 BAU/ml (Abbott), 48 (Beckman), 559 (Roche), and 270 (Siemens). For a reference cutoff of 264 BAU/ml, assays showed moderate to good overall concordance with Genscript: 87% concordance for Abbott, 78% for Beckman, 75% for Roche, and 88% for Siemens. Results: Samples from 69 patients were analyzed. The results were compared to the percent inhibition calculated using a functional surrogate of a standardized virus neutralization test (Genscript). Methods: This study was performed on data retrieved from 69 individuals, who received at least one dose of the Pfizer/BioNTech BNT162b2 or Moderna COVID-19 vaccine (Spikevax) at the Alphabio Laboratory in Marseille, France (European Hospital, Alphabio – Biogroup). The aim was to assess the threshold of 264 binding antibody units (BAU)/ml using four different SARS-CoV-2 antibody assays (Abbott, Beckman, Roche, and Siemens) and to establish a new optimal threshold of protection for each of the four antibody assays. ![]() Background: Identifying a specific threshold level of SARS-CoV-2 antibodies that confers protection in immunocompromised patients has been very challenging.
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